1. start or arrange something, make someone look guilty of a crime
set up a business/deal
Set up has a number of uses and meanings. As a noun, a 'set up' refers to how things are arranged or positioned, usually in a way that is optimal for items to be used. "Are you comfortable working in an open plan set up?" A 'set up' can also refer to a group or organisation. "I joined a set-up of environmental enthusiasts." A 'set up' can also be a scheme, arrangement or trick intended to humiliate or deceive someone. "I don't believe he is guilty, I believe it was a setup." As a verb 'to set someone up' can mean to provide for someone so that they can achieve a goal. "Her parents have set her up with a college fund." In an informal context, you might use 'set up' to mean to make someone ready or prepared or refreshed. "That lunch set me up for the busy afternoon ahead." To 'set up' someone can mean to arrange things so someone appears guilty or in order to trick someone in a humorous or harmful way. "He was set up in an elaborate hoax." To 'set up' can also mean to build or place something in a specific way. "Would you help me set up the room for the guests?" You can also 'set up' machinery or equipment so that it is ready to use. "The band have everything set up and are ready to play." You can also 'set up' a meeting, for example, meaning you have made arrangements or plans for something to happen. If you 'set up a project' it means to begin it or to start a process.