strongly dislike and have a low opinion of somebody or something
despise - hate
To ‘despise’ means to feel repugnance or hatred for somebody or something because you believe that that person or thing is awful, has no value, or is beneath you. This word therefore expresses a strong form of contempt and disrespect, which can also be directed at yourself.
Those two parties will never come to an agreement. They despise each other.
For a long time I considered myself despicable because of my addiction, but later I realized that I simply needed help.
I went from loving my job to despising it within a few years. I felt it was bringing too much stress into my life.