befuddle - confuse
The word ‘befuddle’ was originally used to describe the condition of somebody's mind when very drunk. While it can still technically be applied in that sense, it is much more common to see it used to express a more general sense of confusion and bewilderment.
Sarah is a highly gifted tactician and can befuddle even the most capable of opponents with her clever manoeuverings.
When I was explaining how the software works to Alex, he looked a little befuddled, so I started again except with less technical jargon.
I find it hard to hide my utter befuddlement at the situation. It just doesn’t make any logical sense at all.